-What will cause Harry to leave the Dursleys’ early?
-Where will he go for the rest of the summer?
-What will become of 12GP and Sirius’s estate?
-Who will Harry spend time with this summer?
-What will he do this summer, or what will happen to him?
-How will he celebrate his birthday?
2. OWL results and sixth year courses
-How did Harry and each of his friends in his year fare?
-What courses will they each be taking now?
-Did Harry score a high enough Potions OWL? Did Ron?
-Will McGonagall have to intervene for Harry?
-Will either Harry or Ron stick with Divination?
-What will happen with Firenze and Prof. Trelawney?
-Who will be the new DADA teacher?
-Will there be any other changes to the staff?
-What new subject matter might they cover?
3. Voldemort and the Death Eaters
-What will LV’s next move be?
-How will people react now that the truth about LV’s return is known?
-What role will Wormtail play? Will his life debt to Harry come into play in this book?
-What role will Bellatrix play?
-What will become of Lucius and the other imprisoned DE’s?
-Where does the scene with the Dark Mark (shown on the US ed. cover) take place, and why is the Mark being displayed?
-Will we learn more about what happened Oct. 31, 1981?
-Will we learn more about the connection between Harry and LV?
-How will Harry deal with his emotions about Sirius’s death and the prophecy?
-Will Harry tell anyone about the prophecy yet, and if so, who? Who will he tell first?
-Will Harry continue to have dreams/visions of LV, and if so, how will he deal with them?
-Will he continue Occlumency lessons?
-Will Harry learn anything more about his parents or his past in this book? Will he find out how his parents got together?
-Will Harry notice another girl in a more-than-friendly way?
-Will another girl show interest in him?
-Will he get another kiss in this book?
-Will Ginny date Dean Thomas? Will she date someone else?
-Will Ron make a move on Hermione, and if so, how will she react (or vice versa)?
-Will Ron and Hermione become a couple?
-Will Ron and Hermione kiss, and if so, will Harry see it?
-How will Harry react to whatever happens between Ron and Hermione?
-Will there be another formal event?
-Will anything further develop between Bill and Fleur? What about Hagrid and Mme. Maxime?
-What do Hermione and Krum write about? Has she visited him, or will she?
-Who will be the new Captain?
-Who will be the new Beaters?
-Will Harry return as Seeker?
-Will Ron return as Keeper?
-Will Ginny be a new Chaser?
-Who else will be on the team?
-How much of a role will it have in the story?
-What is going on in the scenes depicted on the different covers we’ve seen so far?
-How does Dumbledore mend his relationship with Harry?
-Will he take over giving Harry Occlumency lessons?
-Will he die in this book?
8. The Half-Blood Prince
-Who is he and what is his significance?
9. Sirius, the veil, and death
-Will Harry see Sirius in some form in this book?
-Will he attempt to journey behind the veil?
-Will he repair and use the mirror?
-Will anyone else die in this book?
-Will we find out anything more about the Hogwarts ghosts or ghosts in general?
10. Other characters
-What will happen with Percy?
-What role will Grawp have in the story?
-Will we find out more about Neville's past? What?
-Will we find out more about Snape's past? What?
-Will we find out if there is a particular reason that Snape hates Neville so much?
-Will we find out more about Hagrid's past? What?
-Will the Trio become a Sextet?
-What role will Luna play?
-What will Rita Skeeter do next?
-What will happen to Fudge and the MoM?
-What will happen to Draco, and what is “Draco’s Detour” about?
-Who or what is Felix Felices?
-Who is the lion-like man described in the excerpt that was released earlier?
-Will we see more of Theodore Nott and/or Blaise Zabini? Will there be a “good” Slytherin among Harry’s cohort?
-What will become of Professor Umbridge?
-Will we learn more about Ginny’s possession in CoS?
-Does Ginny owe Harry a life debt? If so, what will become of it?
-Will Ron say Voldemort’s name? Will Harry’s other friends say it?
-Does Grindelwald have any significance in the story?
11. Other subplots and loose ends
-What will happen with SPEW and the House Elves?
-What will happen with the Centaurs? Will any of them take sides in the war like Firenze?
-What role will the Goblins and other magical creatures play?
-Will Hermione learn to apparate after her birthday? Will Ron?
-Will Harry go into the Forbidden Forest this year, and if so, will he see Aragog or the Ford Anglia?
-What is Spinner’s End?
-How will the matter of inter-house relations be addressed?
-Will we find out more about Hogwarts's past (the Founders)? What? Will we learn more about the fall-out between GG and SS?
-Will we learn the identity of the eavesdropper who heard the beginning of the prophecy?
-Will we see the Chamber of Secrets again?
-What other old characters, creatures, spells, concepts, etc will we see again?
Feel free to add more.